Scientists recently discovered that intake of Resveratrol, through wine or Resveratrol supplements, does exactly. If there is a longevity gene, why can't we live to the ripe old age of 200 or 300. First of all, we must define longevity as successful, healthy aging, which of course, is the prerequisite for longevity.
In aging and age-related diseases such as Alzheimer's and Parkinson's, the loss of cells in vital structures or organs may be related to several factors. ROS leads to DNA damage and cell death. While this question is quite compelling, after reading the article title, most people have an even more burning question.
Production of reactive oxygen species (ROS) by mitochondria (energy-producing organelles in the nucleus of a cell). In this case, increasing SIRT 1 has been found to protect cells against amyloid-beta-induced ROS production and DNA damage, thereby reducing cell death. Although a diet rich in antioxidants may offer hope in delaying the onset of age-related diseases, only calorie restriction can extend our lifespan. Somehow, calorie restriction activates the SIRT 1 gene, an enzyme that triggers DNA repair and regulates programmed cell death. Aging is typically characterized by a progressive deterioration of physiological and metabolic processes. |